The new season will begin with a potential Super Bowl preview in the 2022 NFL Kickoff Game as the Los Angeles Rams host the Buffalo Bills in SoFi Stadium. The Rams will hoist their Super Bowl banner during pregame festivities and the Bills are the current 2023 Super Bowl favorites in the NFL odds from Caesars Sportsbook. With so much star power on both sides, NFL DFS players will have their work cut out crafting their NFL DFS lineups.
Cooper Kupp, Stefon Diggs, Matthew Stafford and Josh Allen are just a handful of the players with the potential to put up massive numbers on Thursday, Sept. 8. What options in the NFL DFS player pool have the best individual NFL DFS matchups and who should you use in the multiplier spots in single-game NFL DFS tournaments, cash games and 50-50s? Before setting your NFL DFS lineups for Rams vs. Bills, be sure to check out the NFL DFS advice, strategy and stacks from SportsLine daily fantasy expert Mike McClure.
McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments.
He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.
Now, McClure has turned his attention to Bills vs. Rams in the NFL Opening Kickoff Game and locked in his top daily fantasy football picks. You can only see them by heading to SportsLine.
Top NFL DFS picks for Rams vs. Bills
One of McClure’s top NFL DFS picks for the NFL Kickoff Game is Rams wide receiver Cooper Kupp. Now entering his sixth season, Kupp is one of the hottest commodities in all fantasy football formats after winning AP NFL Offensive Player of the Year honors with a historic receiving season.
Kupp caught 145 passes for 1,947 yards and 16 touchdowns in 17 games. He followed that up by catching 33 passes for 478 yards and six touchdowns in four postseason games, winning Super Bowl MVP honors.
Part of McClure’s optimal NFL DFS strategy also includes rostering Bills quarterback Josh Allen. The No. 7 overall pick in the 2018 NFL Draft had a pretty pedestrian rookie season but showed some growth in his second year before breaking out in Year Three. Allen has now thrown for 8,951 yards and 73 touchdowns while throwing just 25 interceptions over the last two seasons and has established himself as a serious threat from the pocket in addition to being one of the best athletes at his position.
Allen has rushed for 2,325 yards and 31 touchdowns in his four seasons in Buffalo and even added a receiving touchdown last season, so he has the ability to impact the game in a number of ways on opening night. See the rest of McClure’s NFL DFS player pool here.
How to set NFL DFS lineups for Bills vs. Rams
McClure is also targeting an undervalued player who is set to explode for huge numbers in the 2022 NFL Kickoff Game. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here.
So who is Mike McClure putting in his optimal NFL DFS lineups for the NFL Kickoff Game 2022? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a daily Fantasy expert with nearly $2 million in winnings, and find out.