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2022 MLB odds, picks, bets for Wednesday, Aug. 17 from proven model: This four-way parlay pays well over 20-1

The Baltimore Orioles can overtake the Toronto Blue Jays for the third and final AL wild card spot when the two teams collide in the last contest of a three-game series on Wednesday. The Orioles (61-55) have won the first two games of the series and trail the Blue Jays (61-54) by a half-game in the American League standings. Toronto is a -170 favorite in the latest Blue Jays vs. Orioles odds from Caesars Sportsbook while Baltimore is a +143 underdog.

First pitch is set for 3:07 pm ET at the Rogers Center in Toronto. The game is one of 15 on the MLB schedule for Wednesday. Elsewhere in the majors, the Mets and Braves meet in the third game of their important four-game series in Atlanta, and Tony Gonsolin looks to become the National League’s first 15-game winner, against the Brewers. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine’s proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is a 300-260 on top-rated MLB money-line picks since the start of the 2021 season. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win the World Series. Anyone who has followed the model has seen profitable returns.

Now, the model has locked in four confident MLB best bets for Wednesday. They all involve games at 7:10 pm ET or later, so there’s still time to get these MLB picks in. If you successfully parlay the picks, you’d be looking at a payout of well over 20-1. You can see the model’s MLB picks only at SportsLine.

Top MLB picks today

After simulating every game on Wednesday 10,000 times, the model is high on the White Sox (+122) to beat the Astros. Chicago (61-56) enters the game on a roll, having won five in a row and seven straight at Guaranteed Rate Field in Chicago. Meanwhile, Houston (75-43) has dropped the first two games of the series to the White Sox.

Chicago starter Michael Kopech (4-8, 3.18 ERA) is coming off his best start of the season. On Friday against the Tigers, the hard-throwing righty threw six no-hit innings and struck out a career-high 11 in the White Sox’ 2-0 win. Chicago is 4-2 in his last six starts. See who else to back right here.

Featured Game | Chicago White Sox vs. Houston Astros

How to make MLB picks and parlays for Wednesday

The model also locked in three other best bets for Wednesday, including a play on a big National League underdog. You can see the model’s MLB Wednesday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of well over 20-1? And what underdog does the model like on Wednesday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 300-260 run on top-rated MLB money-line picks since the start of 2021.