Skip to content

2022 MLB odds, picks, bets for Friday, Sept. 23 from proven model: This four-way parlay pays well over 8-1

  • by

Slugger Aaron Judge resumes his pursuit of both the American League single-season home run record and the Triple Crown when he and the New York Yankees (91-58) take on the rival Boston Red Sox (72-77) on Friday. Judge just missed hitting home run No. 61 on Thursday, but he also leads the AL in RBI (128) and batting average (.316). New York is a -235 favorite in the latest Yankees vs. Red Sox odds from Caesars Sportsbook, while Boston is a +192 underdog. The over/under for runs scored is 7.5.

First pitch is set for 7:05 pm ET from Yankee Stadium in the Bronx, NY The game is one of 15 on the MLB schedule for Friday. Elsewhere in the majors, the Cardinals’ Albert Pujols continues his pursuit of career home run No. 700, against the Dodgers, and the Rays and Blue Jays collide in Tampa, Fla. Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine’s proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 321-272 on top-rated MLB money-line picks since the start of the 2021 season, returning more than $600 for $100 bettors during that span. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anyone who has followed it has seen profitable returns.

Now, the model has locked in four confident MLB best bets for Friday. They all involve games at 7:05 pm ET or later, so there’s still time to get these MLB picks in. If you successfully parlay the picks, you’d be looking at a payout of well over 8-1. You can only see the model’s MLB picks at SportsLine.

Top MLB picks today

After simulating every game on Friday 10,000 times, the model is high on the Rays (-145) to beat the Blue Jays. Tampa Bay (83-67) whipped Toronto, 10-5, on Thursday to pull within one game of the Blue Jays (84-66) for the lead in the AL wild card race. The Rays lead the season series between the teams, 9-7, and have the edge over the last three seasons, 26-19.

Tampa Bay starter Jeffrey Springs has been on a roll recently. In September, the 30-year-old lefty is 3-0 and has allowed just two earned runs while striking out 20 in 20.1 innings (0.89 ERA). On Sept. 13, he pitched six scoreless innings and allowed just three hits to Toronto. See who else to back right here.

Featured Game | Tampa Bay Rays vs. Toronto Blue Jays

How to make MLB picks and parlays for Friday

The model also locked in three other best bets for Friday, including a play on a big NL underdog. You can see the model’s MLB Friday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of well over 8-1? And what underdog does the model like on Friday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 321-272 run on top-rated MLB money-line picks since the start of 2021.